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	<title>Disinformation &#187; stress</title>
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		<title>Scientists Develop A Vaccine For Stress</title>
		<link>http://www.disinfo.com/2010/08/scientists-develop-a-vaccine-for-stress/</link>
		<comments>http://www.disinfo.com/2010/08/scientists-develop-a-vaccine-for-stress/#comments</comments>
		<pubDate>Mon, 16 Aug 2010 15:58:47 +0000</pubDate>
		<dc:creator>JacobSloan</dc:creator>
				<category><![CDATA[News]]></category>
		<category><![CDATA[Brain]]></category>
		<category><![CDATA[Health]]></category>
		<category><![CDATA[Medicine]]></category>
		<category><![CDATA[Psychology]]></category>
		<category><![CDATA[stress]]></category>
		<category><![CDATA[Vaccines]]></category>

		<guid isPermaLink="false">http://www.disinfo.com/?p=34398</guid>
		<description><![CDATA[<p><a href="http://www.cbsnews.com/8301-504763_162-20012469-10391704.html"><img class="alignright size-full wp-image-34399" title="drsapolsky-512_370x278" src="http://disinfo.s3.amazonaws.com/wp-content/uploads/2010/08/drsapolsky-512_370x2781.jpg" alt="drsapolsky-512_370x278" width="235" /></a>Is this a step on the path to a <em>Brave New World</em>? The head of a research team at Stanford says he is on the verge of producing a vaccine that would deactivate the brain&#8217;s stress-causing chemicals. For the first time, people could shut off the fight-or-flight mechanism that has determined our behavior (and helped ensure our survival) since the caveman era. Via <a href="http://www.cbsnews.com/8301-504763_162-20012469-10391704.html">CBS News</a>:</p>
<blockquote><p>Dr Robert Sapolsky, a neuroscience professor at Stanford, says after 30 years of studying stress, his team might be on the verge of a novel cure.</p>
<p>Sapolsky has long theorized that, unlike some animals, humans are unable to turn off stress chemicals used for the fight-or-flight mechanism. A class of hormone called glucocorticoids are one of the chief offenders, according to Sapolsky.</p>
<p>So his team has pioneered a way to bootstrap a &#8220;herpes virus to carry engineered &#8216;neuroprotective&#8217; genes deep into the brain to neutralize the rogue hormones&#8230;</p></blockquote>]]></description>
			<content:encoded><![CDATA[<p><a href="http://www.cbsnews.com/8301-504763_162-20012469-10391704.html"><img class="alignright size-full wp-image-34399" title="drsapolsky-512_370x278" src="http://disinfo.s3.amazonaws.com/wp-content/uploads/2010/08/drsapolsky-512_370x2781.jpg" alt="drsapolsky-512_370x278" width="235" /></a>Is this a step on the path to a <em>Brave New World</em>? The head of a research team at Stanford says he is on the verge of producing a vaccine that would deactivate the brain&#8217;s stress-causing chemicals. For the first time, people could shut off the fight-or-flight mechanism that has determined our behavior (and helped ensure our survival) since the caveman era. Via <a href="http://www.cbsnews.com/8301-504763_162-20012469-10391704.html">CBS News</a>:</p>
<blockquote><p>Dr Robert Sapolsky, a neuroscience professor at Stanford, says after 30 years of studying stress, his team might be on the verge of a novel cure.</p>
<p>Sapolsky has long theorized that, unlike some animals, humans are unable to turn off stress chemicals used for the fight-or-flight mechanism. A class of hormone called glucocorticoids are one of the chief offenders, according to Sapolsky.</p>
<p>So his team has pioneered a way to bootstrap a &#8220;herpes virus to carry engineered &#8216;neuroprotective&#8217; genes deep into the brain to neutralize the rogue hormones before they can cause damage.&#8221;</p>
<p>So far, rat studies have gone well, according to the British paper. Human trials are still years away.</p></blockquote>
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		<slash:comments>16</slash:comments>
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		<item>
		<title>Early Life Stress Has Effects at the Molecular Level</title>
		<link>http://www.disinfo.com/2009/11/early-life-stress-has-effects-at-the-molecular-level/</link>
		<comments>http://www.disinfo.com/2009/11/early-life-stress-has-effects-at-the-molecular-level/#comments</comments>
		<pubDate>Sun, 15 Nov 2009 13:36:01 +0000</pubDate>
		<dc:creator>phunkychic666</dc:creator>
				<category><![CDATA[News]]></category>
		<category><![CDATA[Science & Technology]]></category>
		<category><![CDATA[stress]]></category>

		<guid isPermaLink="false">http://www.disinfo.com/?p=14626</guid>
		<description><![CDATA[<p>by Lin Edwards in <a href="http://www.physorg.com/news177227567.html">PhysOrg.com</a>:</p>
<blockquote><p>A new study of mice suggests that stress and trauma in early life can have an impact on the genes and result in behavioral problems later in life.</p>
<p>Scientists from the Max Planck Institute of Psychiatry in Munich, Germany, looked at the long-term effects of stress mice suffered soon after their birth. The stress was produced by separating the mouse pups from their mothers for three hours a day for the first ten days of their lives. The separation did not affect their nutrition but would have made them feel abandoned. The pups were then followed through their lives.</p>
<p>The researchers found the stress caused the baby mice to produce hormones that altered their genes and affected their later behavior, making them less able to cope with stress later in life. The mice exposed to the stresses also had poorer memories than the control group.</p>
<p>The leader of the&#8230;</p></blockquote>]]></description>
			<content:encoded><![CDATA[<p>by Lin Edwards in <a href="http://www.physorg.com/news177227567.html">PhysOrg.com</a>:</p>
<blockquote><p>A new study of mice suggests that stress and trauma in early life can have an impact on the genes and result in behavioral problems later in life.</p>
<p>Scientists from the Max Planck Institute of Psychiatry in Munich, Germany, looked at the long-term effects of stress mice suffered soon after their birth. The stress was produced by separating the mouse pups from their mothers for three hours a day for the first ten days of their lives. The separation did not affect their nutrition but would have made them feel abandoned. The pups were then followed through their lives.</p>
<p>The researchers found the stress caused the baby mice to produce hormones that altered their genes and affected their later behavior, making them less able to cope with stress later in life. The mice exposed to the stresses also had poorer memories than the control group.</p>
<p>The leader of the team, Dr Christopher Murgatroyd, told the BBC that the research for the first time showed in molecular detail how stress in early life could program behavior later on. The stress had caused the animals to produce high levels of stress hormones, and this in turn had led to epigenetic changes, meaning that the experience had changed the DNA of a gene coding for the stress hormone vasopressin, which is important in controlling mood and cognitive behaviors. The result of the genetic changes meant the brain developed more receptors for vasopressin.</p></blockquote>
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